diff --git a/Marlin/Configuration.h b/Marlin/Configuration.h
index 58cb251488..366267aa7e 100644
--- a/Marlin/Configuration.h
+++ b/Marlin/Configuration.h
@@ -105,21 +105,9 @@
 #define SERIAL_PORT 0
 
 /**
- * Select a secondary serial port on the board to use for communication with the host.
- * Currently Ethernet (-2) is only supported on Teensy 4.1 boards.
- * :[-2, -1, 0, 1, 2, 3, 4, 5, 6, 7]
- */
-//#define SERIAL_PORT_2 -1
-
-/**
- * Select a third serial port on the board to use for communication with the host.
- * Currently only supported for AVR, DUE, LPC1768/9 and STM32/STM32F1
- * :[-1, 0, 1, 2, 3, 4, 5, 6, 7]
- */
-//#define SERIAL_PORT_3 1
-
-/**
- * This setting determines the communication speed of the printer.
+ * Serial Port Baud Rate
+ * This is the default communication speed for all serial ports.
+ * Set the baud rate defaults for additional serial ports below.
  *
  * 250000 works in most cases, but you might try a lower speed if
  * you commonly experience drop-outs during host printing.
@@ -128,6 +116,23 @@
  * :[2400, 9600, 19200, 38400, 57600, 115200, 250000, 500000, 1000000]
  */
 #define BAUDRATE 250000
+//#define BAUD_RATE_GCODE     // Enable G-code M575 to set the baud rate
+
+/**
+ * Select a secondary serial port on the board to use for communication with the host.
+ * Currently Ethernet (-2) is only supported on Teensy 4.1 boards.
+ * :[-2, -1, 0, 1, 2, 3, 4, 5, 6, 7]
+ */
+//#define SERIAL_PORT_2 -1
+//#define BAUDRATE_2 250000   // Enable to override BAUDRATE
+
+/**
+ * Select a third serial port on the board to use for communication with the host.
+ * Currently only supported for AVR, DUE, LPC1768/9 and STM32/STM32F1
+ * :[-1, 0, 1, 2, 3, 4, 5, 6, 7]
+ */
+//#define SERIAL_PORT_3 1
+//#define BAUDRATE_3 250000   // Enable to override BAUDRATE
 
 // Enable the Bluetooth serial interface on AT90USB devices
 //#define BLUETOOTH
diff --git a/Marlin/Configuration_adv.h b/Marlin/Configuration_adv.h
index 5335fa012a..5db36d9cbb 100644
--- a/Marlin/Configuration_adv.h
+++ b/Marlin/Configuration_adv.h
@@ -2114,9 +2114,6 @@
   //#define SERIAL_XON_XOFF
 #endif
 
-// Add M575 G-code to change the baud rate
-//#define BAUD_RATE_GCODE
-
 #if ENABLED(SDSUPPORT)
   // Enable this option to collect and display the maximum
   // RX queue usage after transferring a file to SD.
diff --git a/Marlin/src/MarlinCore.cpp b/Marlin/src/MarlinCore.cpp
index 5ef575a30f..4fca64ba6b 100644
--- a/Marlin/src/MarlinCore.cpp
+++ b/Marlin/src/MarlinCore.cpp
@@ -1073,11 +1073,17 @@ void setup() {
   while (!MYSERIAL1.connected() && PENDING(millis(), serial_connect_timeout)) { /*nada*/ }
 
   #if HAS_MULTI_SERIAL && !HAS_ETHERNET
-    MYSERIAL2.begin(BAUDRATE);
+    #ifndef BAUDRATE_2
+      #define BAUDRATE_2 BAUDRATE
+    #endif
+    MYSERIAL2.begin(BAUDRATE_2);
     serial_connect_timeout = millis() + 1000UL;
     while (!MYSERIAL2.connected() && PENDING(millis(), serial_connect_timeout)) { /*nada*/ }
     #ifdef SERIAL_PORT_3
-      MYSERIAL3.begin(BAUDRATE);
+      #ifndef BAUDRATE_3
+        #define BAUDRATE_3 BAUDRATE
+      #endif
+      MYSERIAL3.begin(BAUDRATE_3);
       serial_connect_timeout = millis() + 1000UL;
       while (!MYSERIAL3.connected() && PENDING(millis(), serial_connect_timeout)) { /*nada*/ }
     #endif
diff --git a/buildroot/tests/STM32F103RC_btt_USB b/buildroot/tests/STM32F103RC_btt_USB
index 8381de0ea6..fb0f2f5bd2 100755
--- a/buildroot/tests/STM32F103RC_btt_USB
+++ b/buildroot/tests/STM32F103RC_btt_USB
@@ -10,7 +10,7 @@ set -e
 # Build with the default configurations
 #
 restore_configs
-opt_set MOTHERBOARD BOARD_BTT_SKR_MINI_V1_1 SERIAL_PORT 1 SERIAL_PORT_2 -1
+opt_set MOTHERBOARD BOARD_BTT_SKR_MINI_V1_1 SERIAL_PORT 1 SERIAL_PORT_2 -1 BAUDRATE_2 115200
 exec_test $1 $2 "BigTreeTech SKR Mini v1.1 - Basic Configuration" "$3"
 
 # clean up