diff --git a/Marlin/Configuration_adv.h b/Marlin/Configuration_adv.h
index 95e93eb288..fa1b470ab2 100644
--- a/Marlin/Configuration_adv.h
+++ b/Marlin/Configuration_adv.h
@@ -1478,6 +1478,15 @@
   // Enable if SD detect is rendered useless (e.g., by using an SD extender)
   //#define NO_SD_DETECT
 
+  // Multiple volume support - EXPERIMENTAL.
+  //#define MULTI_VOLUME
+  #if ENABLED(MULTI_VOLUME)
+    #define VOLUME_SD_ONBOARD
+    #define VOLUME_USB_FLASH_DRIVE
+    #define DEFAULT_VOLUME SD_ONBOARD
+    #define DEFAULT_SHARED_VOLUME USB_FLASH_DRIVE
+  #endif
+
 #endif // SDSUPPORT
 
 /**
diff --git a/Marlin/src/HAL/DUE/usb/sd_mmc_spi_mem.cpp b/Marlin/src/HAL/DUE/usb/sd_mmc_spi_mem.cpp
index d92d332c1e..3dcbbaecd2 100644
--- a/Marlin/src/HAL/DUE/usb/sd_mmc_spi_mem.cpp
+++ b/Marlin/src/HAL/DUE/usb/sd_mmc_spi_mem.cpp
@@ -32,7 +32,7 @@ Ctrl_status sd_mmc_spi_test_unit_ready() {
 Ctrl_status sd_mmc_spi_read_capacity(uint32_t *nb_sector) {
   if (!IS_SD_INSERTED() || IS_SD_PRINTING() || IS_SD_FILE_OPEN() || !card.isMounted())
     return CTRL_NO_PRESENT;
-  *nb_sector = card.getSd2Card().cardSize() - 1;
+  *nb_sector = card.diskIODriver()->cardSize() - 1;
   return CTRL_GOOD;
 }
 
@@ -74,24 +74,24 @@ Ctrl_status sd_mmc_spi_usb_read_10(uint32_t addr, uint16_t nb_sector) {
   #endif
 
   // Start reading
-  if (!card.getSd2Card().readStart(addr))
+  if (!card.diskIODriver()->readStart(addr))
     return CTRL_FAIL;
 
   // For each specified sector
   while (nb_sector--) {
 
     // Read a sector
-    card.getSd2Card().readData(sector_buf);
+    card.diskIODriver()->readData(sector_buf);
 
     // RAM -> USB
     if (!udi_msc_trans_block(true, sector_buf, SD_MMC_BLOCK_SIZE, nullptr)) {
-      card.getSd2Card().readStop();
+      card.diskIODriver()->readStop();
       return CTRL_FAIL;
     }
   }
 
   // Stop reading
-  card.getSd2Card().readStop();
+  card.diskIODriver()->readStop();
 
   // Done
   return CTRL_GOOD;
@@ -113,7 +113,7 @@ Ctrl_status sd_mmc_spi_usb_write_10(uint32_t addr, uint16_t nb_sector) {
   }
   #endif
 
-  if (!card.getSd2Card().writeStart(addr, nb_sector))
+  if (!card.diskIODriver()->writeStart(addr, nb_sector))
     return CTRL_FAIL;
 
   // For each specified sector
@@ -121,16 +121,16 @@ Ctrl_status sd_mmc_spi_usb_write_10(uint32_t addr, uint16_t nb_sector) {
 
     // USB -> RAM
     if (!udi_msc_trans_block(false, sector_buf, SD_MMC_BLOCK_SIZE, nullptr)) {
-      card.getSd2Card().writeStop();
+      card.diskIODriver()->writeStop();
       return CTRL_FAIL;
     }
 
     // Write a sector
-    card.getSd2Card().writeData(sector_buf);
+    card.diskIODriver()->writeData(sector_buf);
   }
 
   // Stop writing
-  card.getSd2Card().writeStop();
+  card.diskIODriver()->writeStop();
 
   // Done
   return CTRL_GOOD;
diff --git a/Marlin/src/HAL/STM32/msc_sd.cpp b/Marlin/src/HAL/STM32/msc_sd.cpp
index 63ce7808f1..20e1ab3cf9 100644
--- a/Marlin/src/HAL/STM32/msc_sd.cpp
+++ b/Marlin/src/HAL/STM32/msc_sd.cpp
@@ -30,54 +30,66 @@
 
 class Sd2CardUSBMscHandler : public USBMscHandler {
 public:
+  DiskIODriver* diskIODriver() {
+    #if ENABLED(MULTI_VOLUME)
+      #if SHARED_VOLUME_IS(SD_ONBOARD)
+        return &card.media_sd_spi;
+      #elif SHARED_VOLUME_IS(USB_FLASH_DRIVE)
+        return &card.media_usbFlashDrive;
+      #endif
+    #else
+      return diskIODriver();
+    #endif
+  }
+
   bool GetCapacity(uint32_t *pBlockNum, uint16_t *pBlockSize) {
-    *pBlockNum = card.getSd2Card().cardSize();
+    *pBlockNum = diskIODriver()->cardSize();
     *pBlockSize = BLOCK_SIZE;
     return true;
   }
 
   bool Write(uint8_t *pBuf, uint32_t blkAddr, uint16_t blkLen) {
-    auto sd2card = card.getSd2Card();
+    auto sd2card = diskIODriver();
     // single block
     if (blkLen == 1) {
       watchdog_refresh();
-      sd2card.writeBlock(blkAddr, pBuf);
+      sd2card->writeBlock(blkAddr, pBuf);
       return true;
     }
 
     // multi block optmization
-    sd2card.writeStart(blkAddr, blkLen);
+    sd2card->writeStart(blkAddr, blkLen);
     while (blkLen--) {
       watchdog_refresh();
-      sd2card.writeData(pBuf);
+      sd2card->writeData(pBuf);
       pBuf += BLOCK_SIZE;
     }
-    sd2card.writeStop();
+    sd2card->writeStop();
     return true;
   }
 
   bool Read(uint8_t *pBuf, uint32_t blkAddr, uint16_t blkLen) {
-    auto sd2card = card.getSd2Card();
+    auto sd2card = diskIODriver();
     // single block
     if (blkLen == 1) {
       watchdog_refresh();
-      sd2card.readBlock(blkAddr, pBuf);
+      sd2card->readBlock(blkAddr, pBuf);
       return true;
     }
 
     // multi block optmization
-    sd2card.readStart(blkAddr);
+    sd2card->readStart(blkAddr);
     while (blkLen--) {
       watchdog_refresh();
-      sd2card.readData(pBuf);
+      sd2card->readData(pBuf);
       pBuf += BLOCK_SIZE;
     }
-    sd2card.readStop();
+    sd2card->readStop();
     return true;
   }
 
   bool IsReady() {
-    return card.isMounted();
+    return diskIODriver()->isReady();
   }
 };
 
@@ -105,8 +117,8 @@ USBMscHandler *pSingleMscHandler = &usbMscHandler;
 void MSC_SD_init() {
   USBDevice.end();
   delay(200);
-  USBDevice.begin();
   USBDevice.registerMscHandlers(1, &pSingleMscHandler, Marlin_STORAGE_Inquirydata);
+  USBDevice.begin();
 }
 
 #endif // __STM32F1__ && HAS_SD_HOST_DRIVE
diff --git a/Marlin/src/MarlinCore.cpp b/Marlin/src/MarlinCore.cpp
index 738f9a8d78..842429a407 100644
--- a/Marlin/src/MarlinCore.cpp
+++ b/Marlin/src/MarlinCore.cpp
@@ -757,7 +757,7 @@ void idle(TERN_(ADVANCED_PAUSE_FEATURE, bool no_stepper_sleep/*=false*/)) {
   TERN_(SDSUPPORT, card.manage_media());
 
   // Handle USB Flash Drive insert / remove
-  TERN_(USB_FLASH_DRIVE_SUPPORT, Sd2Card::idle());
+  TERN_(USB_FLASH_DRIVE_SUPPORT, card.diskIODriver()->idle());
 
   // Announce Host Keepalive state (if any)
   TERN_(HOST_KEEPALIVE_FEATURE, gcode.host_keepalive());
diff --git a/Marlin/src/inc/Conditionals_adv.h b/Marlin/src/inc/Conditionals_adv.h
index 3bd77d7545..735e6464d9 100644
--- a/Marlin/src/inc/Conditionals_adv.h
+++ b/Marlin/src/inc/Conditionals_adv.h
@@ -245,7 +245,7 @@
   #define _CUTTER_POWER_PERCENT 2
   #define _CUTTER_POWER_RPM     3
   #define _CUTTER_POWER(V)      _CAT(_CUTTER_POWER_, V)
-  #define CUTTER_UNIT_IS(V)    (_CUTTER_POWER(CUTTER_POWER_UNIT)    == _CUTTER_POWER(V))
+  #define CUTTER_UNIT_IS(V)    (_CUTTER_POWER(CUTTER_POWER_UNIT) == _CUTTER_POWER(V))
 #endif
 
 // Add features that need hardware PWM here
diff --git a/Marlin/src/inc/Conditionals_post.h b/Marlin/src/inc/Conditionals_post.h
index 337cf2a950..f00dd6ec97 100644
--- a/Marlin/src/inc/Conditionals_post.h
+++ b/Marlin/src/inc/Conditionals_post.h
@@ -356,6 +356,15 @@
       #define SD_DETECT_STATE LOW
     #endif
   #endif
+
+  #if DISABLED(USB_FLASH_DRIVE_SUPPORT) || BOTH(MULTI_VOLUME, VOLUME_SD_ONBOARD)
+    #if ENABLED(SDIO_SUPPORT)
+      #define NEED_SD2CARD_SDIO 1
+    #else
+      #define NEED_SD2CARD_SPI 1
+    #endif
+  #endif
+
 #endif
 
 #if ANY(HAS_GRAPHICAL_TFT, LCD_USE_DMA_FSMC, HAS_FSMC_GRAPHICAL_TFT, HAS_SPI_GRAPHICAL_TFT) || !PIN_EXISTS(SD_DETECT)
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/draw_keyboard.cpp b/Marlin/src/lcd/extui/lib/mks_ui/draw_keyboard.cpp
index a05c558beb..3572991813 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/draw_keyboard.cpp
+++ b/Marlin/src/lcd/extui/lib/mks_ui/draw_keyboard.cpp
@@ -148,7 +148,7 @@ static void lv_kb_event_cb(lv_obj_t *kb, lv_event_t event) {
             public_buf_l[6] = 0x00;
             raw_send_to_wifi((uint8_t*)public_buf_l, 6);
 
-            last_disp_state = KEY_BOARD_UI;
+            last_disp_state = KEYBOARD_UI;
             lv_clear_keyboard();
             wifi_tips_type = TIPS_TYPE_JOINING;
             lv_draw_wifi_tips();
@@ -216,7 +216,7 @@ static void lv_kb_event_cb(lv_obj_t *kb, lv_event_t event) {
 }
 
 void lv_draw_keyboard() {
-  scr = lv_screen_create(KEY_BOARD_UI, "");
+  scr = lv_screen_create(KEYBOARD_UI, "");
 
   // Create styles for the keyboard
   static lv_style_t rel_style, pr_style;
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/draw_media_select.cpp b/Marlin/src/lcd/extui/lib/mks_ui/draw_media_select.cpp
new file mode 100644
index 0000000000..6dc816cc23
--- /dev/null
+++ b/Marlin/src/lcd/extui/lib/mks_ui/draw_media_select.cpp
@@ -0,0 +1,73 @@
+/**
+ * Marlin 3D Printer Firmware
+ * Copyright (c) 2021 MarlinFirmware [https://github.com/MarlinFirmware/Marlin]
+ *
+ * Based on Sprinter and grbl.
+ * Copyright (c) 2011 Camiel Gubbels / Erik van der Zalm
+ *
+ * This program is free software: you can redistribute it and/or modify
+ * it under the terms of the GNU General Public License as published by
+ * the Free Software Foundation, either version 3 of the License, or
+ * (at your option) any later version.
+ *
+ * This program is distributed in the hope that it will be useful,
+ * but WITHOUT ANY WARRANTY; without even the implied warranty of
+ * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+ * GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License
+ * along with this program.  If not, see <https://www.gnu.org/licenses/>.
+ *
+ */
+#include "../../../../inc/MarlinConfigPre.h"
+
+#if BOTH(HAS_TFT_LVGL_UI, MULTI_VOLUME)
+
+#include "draw_ui.h"
+#include <lv_conf.h>
+
+#include "../../../../inc/MarlinConfig.h"
+#include "../../../../sd/cardreader.h"
+
+extern lv_group_t *g;
+static lv_obj_t *scr;
+
+enum {
+  ID_T_USB_DISK = 1,
+  ID_T_SD_DISK,
+  ID_T_RETURN
+};
+
+#if ENABLED(MKS_TEST)
+  extern uint8_t curent_disp_ui;
+#endif
+
+static void event_handler(lv_obj_t *obj, lv_event_t event) {
+  if (event != LV_EVENT_RELEASED) return;
+  lv_clear_media_select();
+  switch (obj->mks_obj_id) {
+    case ID_T_USB_DISK: card.changeMedia(&card.media_usbFlashDrive); break;
+    case ID_T_SD_DISK:  card.changeMedia(&card.media_sd_spi); break;
+    case ID_T_RETURN:
+      TERN_(MKS_TEST, curent_disp_ui = 1);
+      lv_draw_ready_print();
+      return;
+  }
+  lv_draw_print_file();
+}
+
+void lv_draw_media_select() {
+  scr = lv_screen_create(MEDIA_SELECT_UI);
+  lv_big_button_create(scr, "F:/bmp_sd.bin", media_select_menu.sd_disk, INTERVAL_V, titleHeight, event_handler, ID_T_SD_DISK);
+  lv_big_button_create(scr, "F:/bmp_usb_disk.bin", media_select_menu.usb_disk, BTN_X_PIXEL + INTERVAL_V * 2, titleHeight, event_handler, ID_T_USB_DISK);
+  lv_big_button_create(scr, "F:/bmp_return.bin", common_menu.text_back, BTN_X_PIXEL * 3 + INTERVAL_V * 4, BTN_Y_PIXEL + INTERVAL_H + titleHeight, event_handler, ID_T_RETURN);
+}
+
+void lv_clear_media_select() {
+  #if HAS_ROTARY_ENCODER
+    if (gCfgItems.encoder_enable) lv_group_remove_all_objs(g);
+  #endif
+  lv_obj_del(scr);
+}
+
+#endif // HAS_TFT_LVGL_UI
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/draw_media_select.h b/Marlin/src/lcd/extui/lib/mks_ui/draw_media_select.h
new file mode 100644
index 0000000000..a698714a9d
--- /dev/null
+++ b/Marlin/src/lcd/extui/lib/mks_ui/draw_media_select.h
@@ -0,0 +1,33 @@
+/**
+ * Marlin 3D Printer Firmware
+ * Copyright (c) 2021 MarlinFirmware [https://github.com/MarlinFirmware/Marlin]
+ *
+ * Based on Sprinter and grbl.
+ * Copyright (c) 2011 Camiel Gubbels / Erik van der Zalm
+ *
+ * This program is free software: you can redistribute it and/or modify
+ * it under the terms of the GNU General Public License as published by
+ * the Free Software Foundation, either version 3 of the License, or
+ * (at your option) any later version.
+ *
+ * This program is distributed in the hope that it will be useful,
+ * but WITHOUT ANY WARRANTY; without even the implied warranty of
+ * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+ * GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License
+ * along with this program.  If not, see <https://www.gnu.org/licenses/>.
+ *
+ */
+#pragma once
+
+#ifdef __cplusplus
+  extern "C" { /* C-declarations for C++ */
+#endif
+
+extern void lv_draw_media_select();
+extern void lv_clear_media_select();
+
+#ifdef __cplusplus
+  } /* C-declarations for C++ */
+#endif
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/draw_print_file.cpp b/Marlin/src/lcd/extui/lib/mks_ui/draw_print_file.cpp
index d32851f761..17f5d95d2a 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/draw_print_file.cpp
+++ b/Marlin/src/lcd/extui/lib/mks_ui/draw_print_file.cpp
@@ -177,7 +177,7 @@ static void event_handler(lv_obj_t *obj, lv_event_t event) {
     }
     else {
       lv_clear_print_file();
-      lv_draw_ready_print();
+      TERN(MULTI_VOLUME, lv_draw_media_select(), lv_draw_ready_print());
     }
   }
   else {
@@ -248,6 +248,7 @@ static char test_public_buf_l[40];
 void disp_gcode_icon(uint8_t file_num) {
   uint8_t i;
 
+  // TODO: set current media title?!
   scr = lv_screen_create(PRINT_FILE_UI, "");
 
   // Create image buttons
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/draw_ready_print.cpp b/Marlin/src/lcd/extui/lib/mks_ui/draw_ready_print.cpp
index d02e774b94..09784b5184 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/draw_ready_print.cpp
+++ b/Marlin/src/lcd/extui/lib/mks_ui/draw_ready_print.cpp
@@ -73,7 +73,7 @@ static void event_handler(lv_obj_t *obj, lv_event_t event) {
     case ID_INFO_EXT:  uiCfg.curTempType = 0; lv_draw_preHeat(); break;
     case ID_INFO_BED:  uiCfg.curTempType = 1; lv_draw_preHeat(); break;
     case ID_INFO_FAN:  lv_draw_fan(); break;
-    case ID_PRINT:  lv_draw_print_file(); break;
+    case ID_PRINT: TERN(MULTI_VOLUME, lv_draw_media_select(), lv_draw_print_file()); break;
   }
 }
 
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.cpp b/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.cpp
index 51e187435c..0a99df08e5 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.cpp
+++ b/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.cpp
@@ -447,111 +447,63 @@ char *getDispText(int index) {
   ZERO(public_buf_l);
 
   switch (disp_state_stack._disp_state[index]) {
-    case PRINT_READY_UI:
-      strcpy(public_buf_l, main_menu.title);
-      break;
-    case PRINT_FILE_UI:
-      strcpy(public_buf_l, file_menu.title);
-      break;
+    case PRINT_READY_UI:      strcpy(public_buf_l, main_menu.title); break;
+    case PRINT_FILE_UI:       strcpy(public_buf_l, file_menu.title); break;
     case PRINTING_UI:
-      if (disp_state_stack._disp_state[disp_state_stack._disp_index] == PRINTING_UI
-        #ifndef TFT35
-          || disp_state_stack._disp_state[disp_state_stack._disp_index] == OPERATE_UI
-          || disp_state_stack._disp_state[disp_state_stack._disp_index] == PAUSE_UI
-        #endif
-      )    strcpy(public_buf_l, common_menu.print_special_title);
-      else strcpy(public_buf_l, printing_menu.title);
-      break;
-    case MOVE_MOTOR_UI:
-      strcpy(public_buf_l, move_menu.title);
+      switch (disp_state_stack._disp_state[disp_state_stack._disp_index]) {
+        IF_DISABLED(TFT35, case OPERATE_UI: case PAUSE_UI:)
+        case PRINTING_UI:     strcpy(public_buf_l, common_menu.print_special_title); break;
+        default:              strcpy(public_buf_l, printing_menu.title); break;
+      }
       break;
+    case MOVE_MOTOR_UI:       strcpy(public_buf_l, move_menu.title); break;
     case OPERATE_UI:
-      if (disp_state_stack._disp_state[disp_state_stack._disp_index] == PRINTING_UI
-        #ifndef TFT35
-          || disp_state_stack._disp_state[disp_state_stack._disp_index] == OPERATE_UI
-          || disp_state_stack._disp_state[disp_state_stack._disp_index] == PAUSE_UI
-        #endif
-      )    strcpy(public_buf_l, common_menu.operate_special_title);
-      else strcpy(public_buf_l, operation_menu.title);
+      switch (disp_state_stack._disp_state[disp_state_stack._disp_index]) {
+        IF_DISABLED(TFT35, case OPERATE_UI: case PAUSE_UI:)
+        case PRINTING_UI:     strcpy(public_buf_l, common_menu.operate_special_title); break;
+        default:              strcpy(public_buf_l, operation_menu.title); break;
+      }
       break;
 
     case PAUSE_UI:
-      if (disp_state_stack._disp_state[disp_state_stack._disp_index] == PRINTING_UI
-        || disp_state_stack._disp_state[disp_state_stack._disp_index] == OPERATE_UI
-        || disp_state_stack._disp_state[disp_state_stack._disp_index] == PAUSE_UI
-      )    strcpy(public_buf_l, common_menu.pause_special_title);
-      else strcpy(public_buf_l, pause_menu.title);
-      break;
-
-    case EXTRUSION_UI:
-      strcpy(public_buf_l, extrude_menu.title);
-      break;
-    case CHANGE_SPEED_UI:
-      strcpy(public_buf_l, speed_menu.title);
-      break;
-    case FAN_UI:
-      strcpy(public_buf_l, fan_menu.title);
+      switch (disp_state_stack._disp_state[disp_state_stack._disp_index]) {
+        case OPERATE_UI:
+        case PAUSE_UI:
+        case PRINTING_UI:     strcpy(public_buf_l, common_menu.pause_special_title); break;
+        default:              strcpy(public_buf_l, pause_menu.title); break;
+      }
       break;
+    case EXTRUSION_UI:        strcpy(public_buf_l, extrude_menu.title); break;
+    case CHANGE_SPEED_UI:     strcpy(public_buf_l, speed_menu.title); break;
+    case FAN_UI:              strcpy(public_buf_l, fan_menu.title); break;
     case PRE_HEAT_UI:
-      if ((disp_state_stack._disp_state[disp_state_stack._disp_index - 1] == OPERATE_UI))
-           strcpy(public_buf_l, preheat_menu.adjust_title);
-      else strcpy(public_buf_l, preheat_menu.title);
-      break;
-    case SET_UI:
-      strcpy(public_buf_l, set_menu.title);
-      break;
-    case ZERO_UI:
-      strcpy(public_buf_l, home_menu.title);
-      break;
-    case SPRAYER_UI: break;
-    case MACHINE_UI: break;
-    case LANGUAGE_UI:
-      strcpy(public_buf_l, language_menu.title);
-      break;
-    case ABOUT_UI:
-      strcpy(public_buf_l, about_menu.title);
-      break;
-    case LOG_UI: break;
-    case DISK_UI:
-      strcpy(public_buf_l, filesys_menu.title);
-      break;
-    case DIALOG_UI:
-      strcpy(public_buf_l, common_menu.dialog_confirm_title);
-      break;
-    case WIFI_UI:
-      strcpy(public_buf_l, wifi_menu.title);
+      switch (disp_state_stack._disp_state[disp_state_stack._disp_index]) {
+        case OPERATE_UI:      strcpy(public_buf_l, preheat_menu.adjust_title);
+        default:              strcpy(public_buf_l, preheat_menu.title); break;
+      }
       break;
+    case SET_UI:              strcpy(public_buf_l, set_menu.title); break;
+    case ZERO_UI:             strcpy(public_buf_l, home_menu.title); break;
+    case SPRAYER_UI:          break;
+    case MACHINE_UI:          break;
+    case LANGUAGE_UI:         strcpy(public_buf_l, language_menu.title); break;
+    case ABOUT_UI:            strcpy(public_buf_l, about_menu.title); break;
+    case LOG_UI:              break;
+    case DISK_UI:             strcpy(public_buf_l, filesys_menu.title); break;
+    case DIALOG_UI:           strcpy(public_buf_l, common_menu.dialog_confirm_title); break;
+    case WIFI_UI:             strcpy(public_buf_l, wifi_menu.title); break;
     case MORE_UI:
-    case PRINT_MORE_UI:
-      strcpy(public_buf_l, more_menu.title);
-      break;
-    case FILAMENTCHANGE_UI:
-      strcpy(public_buf_l, filament_menu.title);
-      break;
+    case PRINT_MORE_UI:       strcpy(public_buf_l, more_menu.title); break;
+    case FILAMENTCHANGE_UI:   strcpy(public_buf_l, filament_menu.title); break;
     case LEVELING_UI:
-    case MESHLEVELING_UI:
-      strcpy(public_buf_l, leveling_menu.title);
-      break;
-    case BIND_UI:
-      strcpy(public_buf_l, cloud_menu.title);
-      break;
-    case TOOL_UI:
-      strcpy(public_buf_l, tool_menu.title);
-      break;
-    case WIFI_LIST_UI:
-      #if ENABLED(MKS_WIFI_MODULE)
-        strcpy(public_buf_l, list_menu.title);
-        break;
-      #endif
-    case MACHINE_PARA_UI:
-      strcpy(public_buf_l, MachinePara_menu.title);
-      break;
-    case BABY_STEP_UI:
-      strcpy(public_buf_l, operation_menu.babystep);
-      break;
-    case EEPROM_SETTINGS_UI:
-      strcpy(public_buf_l, eeprom_menu.title);
-      break;
+    case MESHLEVELING_UI:     strcpy(public_buf_l, leveling_menu.title); break;
+    case BIND_UI:             strcpy(public_buf_l, cloud_menu.title); break;
+    case TOOL_UI:             strcpy(public_buf_l, tool_menu.title); break;
+    case WIFI_LIST_UI:        TERN_(MKS_WIFI_MODULE, strcpy(public_buf_l, list_menu.title)); break;
+    case MACHINE_PARA_UI:     strcpy(public_buf_l, MachinePara_menu.title); break;
+    case BABY_STEP_UI:        strcpy(public_buf_l, operation_menu.babystep); break;
+    case EEPROM_SETTINGS_UI:  strcpy(public_buf_l, eeprom_menu.title); break;
+    case MEDIA_SELECT_UI:     strcpy(public_buf_l, media_select_menu.title); break;
     default: break;
   }
 
@@ -828,11 +780,9 @@ void GUI_RefreshPage() {
       }
       break;
 
-    case OPERATE_UI:
-      break;
+    case OPERATE_UI: break;
 
-    case PAUSE_UI:
-      break;
+    case PAUSE_UI: break;
 
     case FAN_UI:
       if (temps_update_flag) {
@@ -841,8 +791,7 @@ void GUI_RefreshPage() {
       }
       break;
 
-    case MOVE_MOTOR_UI:
-      break;
+    case MOVE_MOTOR_UI: break;
 
     #if ENABLED(MKS_WIFI_MODULE)
       case WIFI_UI:
@@ -852,10 +801,9 @@ void GUI_RefreshPage() {
         }
         break;
 
-      case BIND_UI:
-        refresh_bind_ui();
-        break;
+      case BIND_UI: refresh_bind_ui(); break;
     #endif
+
     case FILAMENTCHANGE_UI:
       if (temps_update_flag) {
         temps_update_flag = false;
@@ -866,10 +814,8 @@ void GUI_RefreshPage() {
       filament_dialog_handle();
       TERN_(MKS_WIFI_MODULE, wifi_scan_handle());
       break;
-    case MESHLEVELING_UI:
-      break;
-    case HARDWARE_TEST_UI:
-      break;
+    case MESHLEVELING_UI: break;
+    case HARDWARE_TEST_UI: break;
     case WIFI_LIST_UI:
       #if ENABLED(MKS_WIFI_MODULE)
         if (printing_rate_update_flag) {
@@ -878,8 +824,8 @@ void GUI_RefreshPage() {
         }
       #endif
       break;
-    case KEY_BOARD_UI:
-      break;
+    case KEYBOARD_UI: break;
+
     #if ENABLED(MKS_WIFI_MODULE)
       case WIFI_TIPS_UI:
         switch (wifi_tips_type) {
@@ -932,6 +878,7 @@ void GUI_RefreshPage() {
         disp_z_offset_value();
       }
       break;
+
     default: break;
   }
 
@@ -982,7 +929,7 @@ void clear_cur_ui() {
     #if ENABLED(MKS_WIFI_MODULE)
       case WIFI_LIST_UI:              lv_clear_wifi_list(); break;
     #endif
-    case KEY_BOARD_UI:                lv_clear_keyboard(); break;
+    case KEYBOARD_UI:                 lv_clear_keyboard(); break;
     #if ENABLED(MKS_WIFI_MODULE)
       case WIFI_TIPS_UI:              lv_clear_wifi_tips(); break;
     #endif
@@ -1013,9 +960,9 @@ void clear_cur_ui() {
     case NUMBER_KEY_UI:               lv_clear_number_key(); break;
     case BABY_STEP_UI:                lv_clear_baby_stepping(); break;
     case PAUSE_POS_UI:                lv_clear_pause_position(); break;
-      #if HAS_TRINAMIC_CONFIG
-        case TMC_CURRENT_UI:          lv_clear_tmc_current_settings(); break;
-      #endif
+    #if HAS_TRINAMIC_CONFIG
+      case TMC_CURRENT_UI:            lv_clear_tmc_current_settings(); break;
+    #endif
     case EEPROM_SETTINGS_UI:          lv_clear_eeprom_settings(); break;
     #if HAS_STEALTHCHOP
       case TMC_MODE_UI:               lv_clear_tmc_step_mode_settings(); break;
@@ -1032,6 +979,9 @@ void clear_cur_ui() {
     #if ENABLED(TOUCH_SCREEN_CALIBRATION)
       case TOUCH_CALIBRATION_UI:      lv_clear_touch_calibration_screen(); break;
     #endif
+    #if ENABLED(MULTI_VOLUME)
+      case MEDIA_SELECT_UI:           lv_clear_media_select(); break;
+    #endif
     default: break;
   }
 }
@@ -1087,7 +1037,7 @@ void draw_return_ui() {
       #if ENABLED(MKS_WIFI_MODULE)
         case WIFI_LIST_UI:              lv_draw_wifi_list(); break;
       #endif
-      case KEY_BOARD_UI:                lv_draw_keyboard(); break;
+      case KEYBOARD_UI:                 lv_draw_keyboard(); break;
       #if ENABLED(MKS_WIFI_MODULE)
         case WIFI_TIPS_UI:              lv_draw_wifi_tips(); break;
       #endif
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.h b/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.h
index 6577d80cdf..2809e4e937 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.h
+++ b/Marlin/src/lcd/extui/lib/mks_ui/draw_ui.h
@@ -76,6 +76,7 @@
 #include "draw_homing_sensitivity_settings.h"
 #include "draw_baby_stepping.h"
 #include "draw_keyboard.h"
+#include "draw_media_select.h"
 #include "draw_encoder_settings.h"
 
 #include "../../../../inc/MarlinConfigPre.h"
@@ -289,7 +290,7 @@ typedef enum {
   TOOL_UI,
   HARDWARE_TEST_UI,
   WIFI_LIST_UI,
-  KEY_BOARD_UI,
+  KEYBOARD_UI,
   WIFI_TIPS_UI,
   MACHINE_PARA_UI,
   MACHINE_SETTINGS_UI,
@@ -327,6 +328,7 @@ typedef enum {
   ENCODER_SETTINGS_UI,
   TOUCH_CALIBRATION_UI,
   GCODE_UI,
+  MEDIA_SELECT_UI,
 } DISP_STATE;
 
 typedef struct {
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/pic_manager.cpp b/Marlin/src/lcd/extui/lib/mks_ui/pic_manager.cpp
index 36f276c21b..9318b50d2b 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/pic_manager.cpp
+++ b/Marlin/src/lcd/extui/lib/mks_ui/pic_manager.cpp
@@ -197,6 +197,13 @@ static const char assets[][LONG_FILENAME_LENGTH] = {
     "bmp_cloud.bin",
   #endif
 
+  #if ENABLED(MULTI_VOLUME)
+    "bmp_usb_disk.bin",
+    // "bmp_usb_disk_sel.bin",
+    "bmp_sd.bin",
+    // "bmp_sd_sel.bin",
+  #endif
+
   // Babystep screen
   "bmp_baby_move0_01.bin",
   "bmp_baby_move0_05.bin",
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/tft_Language_en.h b/Marlin/src/lcd/extui/lib/mks_ui/tft_Language_en.h
index 104e1fdcaf..b6eef18368 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/tft_Language_en.h
+++ b/Marlin/src/lcd/extui/lib/mks_ui/tft_Language_en.h
@@ -540,6 +540,7 @@
 #define USB_DRIVE_BACK_EN                 "< Back"
 #define FILE_PAGES_EN                     "%d/%d"
 #define FILE_NEXT_PAGE_EN                 "Next Page"
+#define MEDIA_SELECT_TITLE_EN             "Select Media"
 
 //BUILD PLATE
 #define PLATE_TITLE_EN                    "Build Plate"
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.cpp b/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.cpp
index 20b7d5f606..5e37acb2b4 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.cpp
+++ b/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.cpp
@@ -56,6 +56,7 @@ tool_menu_def                tool_menu;
 MachinePara_menu_def         MachinePara_menu;
 pause_msg_def                pause_msg_menu;
 eeprom_def                   eeprom_menu;
+media_select_menu_def        media_select_menu;
 
 machine_common_def machine_menu;
 void machine_setting_disp() {
@@ -821,6 +822,10 @@ void disp_language_init() {
 
   filament_menu.stat_temp = TEXT_VALUE;
 
+  media_select_menu.title    = MEDIA_SELECT_TITLE_EN;
+  media_select_menu.sd_disk  = SD_CARD_TITLE_EN;
+  media_select_menu.usb_disk = USB_DRIVE_TITLE_EN;
+
   machine_menu.key_0     = KEYBOARD_KEY0_EN;
   machine_menu.key_1     = KEYBOARD_KEY1_EN;
   machine_menu.key_2     = KEYBOARD_KEY2_EN;
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.h b/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.h
index 61e3524c58..79faad74e2 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.h
+++ b/Marlin/src/lcd/extui/lib/mks_ui/tft_multi_language.h
@@ -706,6 +706,14 @@ typedef struct tool_menu_disp {
 
 extern tool_menu_def tool_menu;
 
+typedef struct media_select_menu_disp {
+  const char *title;
+  const char *sd_disk;
+  const char *usb_disk;
+} media_select_menu_def;
+
+extern media_select_menu_def media_select_menu;
+
 typedef struct MachinePara_menu_disp {
   const char *title;
   const char *MachineSetting;
diff --git a/Marlin/src/lcd/extui/lib/mks_ui/wifi_module.cpp b/Marlin/src/lcd/extui/lib/mks_ui/wifi_module.cpp
index 6c2afeafd3..1162f7a228 100644
--- a/Marlin/src/lcd/extui/lib/mks_ui/wifi_module.cpp
+++ b/Marlin/src/lcd/extui/lib/mks_ui/wifi_module.cpp
@@ -1142,7 +1142,7 @@ static void wifi_list_msg_handle(uint8_t * msg, uint16_t msgLen) {
   int8_t valid_name_num;
 
   if (msgLen <= 0) return;
-  if (disp_state == KEY_BOARD_UI) return;
+  if (disp_state == KEYBOARD_UI) return;
 
   wifi_list.getNameNum = msg[0];
 
diff --git a/Marlin/src/sd/Sd2Card.cpp b/Marlin/src/sd/Sd2Card.cpp
index 28049c7e7e..3e714fe9fe 100644
--- a/Marlin/src/sd/Sd2Card.cpp
+++ b/Marlin/src/sd/Sd2Card.cpp
@@ -30,7 +30,7 @@
 
 #include "../inc/MarlinConfig.h"
 
-#if ENABLED(SDSUPPORT) && NONE(USB_FLASH_DRIVE_SUPPORT, SDIO_SUPPORT)
+#if NEED_SD2CARD_SPI
 
 /* Enable FAST CRC computations - You can trade speed for FLASH space if
  * needed by disabling the following define */
@@ -88,7 +88,7 @@
 #endif
 
 // Send command and return error code. Return zero for OK
-uint8_t Sd2Card::cardCommand(const uint8_t cmd, const uint32_t arg) {
+uint8_t DiskIODriver_SPI_SD::cardCommand(const uint8_t cmd, const uint32_t arg) {
   // Select card
   chipSelect();
 
@@ -133,7 +133,7 @@ uint8_t Sd2Card::cardCommand(const uint8_t cmd, const uint32_t arg) {
  * \return The number of 512 byte data blocks in the card
  *         or zero if an error occurs.
  */
-uint32_t Sd2Card::cardSize() {
+uint32_t DiskIODriver_SPI_SD::cardSize() {
   csd_t csd;
   if (!readCSD(&csd)) return 0;
   if (csd.v1.csd_ver == 0) {
@@ -155,12 +155,12 @@ uint32_t Sd2Card::cardSize() {
   }
 }
 
-void Sd2Card::chipDeselect() {
+void DiskIODriver_SPI_SD::chipDeselect() {
   extDigitalWrite(chipSelectPin_, HIGH);
   spiSend(0xFF); // Ensure MISO goes high impedance
 }
 
-void Sd2Card::chipSelect() {
+void DiskIODriver_SPI_SD::chipSelect() {
   spiInit(spiRate_);
   extDigitalWrite(chipSelectPin_, LOW);
 }
@@ -178,7 +178,7 @@ void Sd2Card::chipSelect() {
  *
  * \return true for success, false for failure.
  */
-bool Sd2Card::erase(uint32_t firstBlock, uint32_t lastBlock) {
+bool DiskIODriver_SPI_SD::erase(uint32_t firstBlock, uint32_t lastBlock) {
   if (ENABLED(SDCARD_READONLY)) return false;
 
   csd_t csd;
@@ -216,7 +216,7 @@ bool Sd2Card::erase(uint32_t firstBlock, uint32_t lastBlock) {
  * \return true if single block erase is supported.
  *         false if single block erase is not supported.
  */
-bool Sd2Card::eraseSingleBlockEnable() {
+bool DiskIODriver_SPI_SD::eraseSingleBlockEnable() {
   csd_t csd;
   return readCSD(&csd) ? csd.v1.erase_blk_en : false;
 }
@@ -230,7 +230,7 @@ bool Sd2Card::eraseSingleBlockEnable() {
  * \return true for success, false for failure.
  * The reason for failure can be determined by calling errorCode() and errorData().
  */
-bool Sd2Card::init(const uint8_t sckRateID, const pin_t chipSelectPin) {
+bool DiskIODriver_SPI_SD::init(const uint8_t sckRateID, const pin_t chipSelectPin) {
   #if IS_TEENSY_35_36 || IS_TEENSY_40_41
     chipSelectPin_ = BUILTIN_SDCARD;
     const uint8_t ret = SDHC_CardInit();
@@ -324,10 +324,12 @@ bool Sd2Card::init(const uint8_t sckRateID, const pin_t chipSelectPin) {
   }
   chipDeselect();
 
+  ready = true;
   return setSckRate(sckRateID);
 
   FAIL:
   chipDeselect();
+  ready = false;
   return false;
 }
 
@@ -338,7 +340,7 @@ bool Sd2Card::init(const uint8_t sckRateID, const pin_t chipSelectPin) {
  * \param[out] dst Pointer to the location that will receive the data.
  * \return true for success, false for failure.
  */
-bool Sd2Card::readBlock(uint32_t blockNumber, uint8_t *dst) {
+bool DiskIODriver_SPI_SD::readBlock(uint32_t blockNumber, uint8_t *dst) {
   #if IS_TEENSY_35_36 || IS_TEENSY_40_41
     return 0 == SDHC_CardReadBlock(dst, blockNumber);
   #endif
@@ -378,7 +380,7 @@ bool Sd2Card::readBlock(uint32_t blockNumber, uint8_t *dst) {
  *
  * \return true for success, false for failure.
  */
-bool Sd2Card::readData(uint8_t *dst) {
+bool DiskIODriver_SPI_SD::readData(uint8_t *dst) {
   chipSelect();
   return readData(dst, 512);
 }
@@ -445,7 +447,7 @@ bool Sd2Card::readData(uint8_t *dst) {
   #endif
 #endif // SD_CHECK_AND_RETRY
 
-bool Sd2Card::readData(uint8_t *dst, const uint16_t count) {
+bool DiskIODriver_SPI_SD::readData(uint8_t *dst, const uint16_t count) {
   bool success = false;
 
   const millis_t read_timeout = millis() + SD_READ_TIMEOUT;
@@ -477,7 +479,7 @@ bool Sd2Card::readData(uint8_t *dst, const uint16_t count) {
 }
 
 /** read CID or CSR register */
-bool Sd2Card::readRegister(const uint8_t cmd, void *buf) {
+bool DiskIODriver_SPI_SD::readRegister(const uint8_t cmd, void *buf) {
   uint8_t *dst = reinterpret_cast<uint8_t*>(buf);
   if (cardCommand(cmd, 0)) {
     error(SD_CARD_ERROR_READ_REG);
@@ -497,7 +499,7 @@ bool Sd2Card::readRegister(const uint8_t cmd, void *buf) {
  *
  * \return true for success, false for failure.
  */
-bool Sd2Card::readStart(uint32_t blockNumber) {
+bool DiskIODriver_SPI_SD::readStart(uint32_t blockNumber) {
   if (type() != SD_CARD_TYPE_SDHC) blockNumber <<= 9;
 
   const bool success = !cardCommand(CMD18, blockNumber);
@@ -511,7 +513,7 @@ bool Sd2Card::readStart(uint32_t blockNumber) {
  *
  * \return true for success, false for failure.
  */
-bool Sd2Card::readStop() {
+bool DiskIODriver_SPI_SD::readStop() {
   chipSelect();
   const bool success = !cardCommand(CMD12, 0);
   if (!success) error(SD_CARD_ERROR_CMD12);
@@ -531,7 +533,7 @@ bool Sd2Card::readStop() {
  * \return The value one, true, is returned for success and the value zero,
  * false, is returned for an invalid value of \a sckRateID.
  */
-bool Sd2Card::setSckRate(const uint8_t sckRateID) {
+bool DiskIODriver_SPI_SD::setSckRate(const uint8_t sckRateID) {
   const bool success = (sckRateID <= 6);
   if (success) spiRate_ = sckRateID; else error(SD_CARD_ERROR_SCK_RATE);
   return success;
@@ -542,12 +544,14 @@ bool Sd2Card::setSckRate(const uint8_t sckRateID) {
  * \param[in] timeout_ms Timeout to abort.
  * \return true for success, false for timeout.
  */
-bool Sd2Card::waitNotBusy(const millis_t timeout_ms) {
+bool DiskIODriver_SPI_SD::waitNotBusy(const millis_t timeout_ms) {
   const millis_t wait_timeout = millis() + timeout_ms;
   while (spiRec() != 0xFF) if (ELAPSED(millis(), wait_timeout)) return false;
   return true;
 }
 
+void DiskIODriver_SPI_SD::error(const uint8_t code) { errorCode_ = code; }
+
 /**
  * Write a 512 byte block to an SD card.
  *
@@ -555,7 +559,7 @@ bool Sd2Card::waitNotBusy(const millis_t timeout_ms) {
  * \param[in] src Pointer to the location of the data to be written.
  * \return true for success, false for failure.
  */
-bool Sd2Card::writeBlock(uint32_t blockNumber, const uint8_t *src) {
+bool DiskIODriver_SPI_SD::writeBlock(uint32_t blockNumber, const uint8_t *src) {
   if (ENABLED(SDCARD_READONLY)) return false;
 
   #if IS_TEENSY_35_36 || IS_TEENSY_40_41
@@ -586,7 +590,7 @@ bool Sd2Card::writeBlock(uint32_t blockNumber, const uint8_t *src) {
  * \param[in] src Pointer to the location of the data to be written.
  * \return true for success, false for failure.
  */
-bool Sd2Card::writeData(const uint8_t *src) {
+bool DiskIODriver_SPI_SD::writeData(const uint8_t *src) {
   if (ENABLED(SDCARD_READONLY)) return false;
 
   bool success = true;
@@ -601,7 +605,7 @@ bool Sd2Card::writeData(const uint8_t *src) {
 }
 
 // Send one block of data for write block or write multiple blocks
-bool Sd2Card::writeData(const uint8_t token, const uint8_t *src) {
+bool DiskIODriver_SPI_SD::writeData(const uint8_t token, const uint8_t *src) {
   if (ENABLED(SDCARD_READONLY)) return false;
 
   const uint16_t crc = TERN(SD_CHECK_AND_RETRY, CRC_CCITT(src, 512), 0xFFFF);
@@ -629,7 +633,7 @@ bool Sd2Card::writeData(const uint8_t token, const uint8_t *src) {
  *
  * \return true for success, false for failure.
  */
-bool Sd2Card::writeStart(uint32_t blockNumber, const uint32_t eraseCount) {
+bool DiskIODriver_SPI_SD::writeStart(uint32_t blockNumber, const uint32_t eraseCount) {
   if (ENABLED(SDCARD_READONLY)) return false;
 
   bool success = false;
@@ -650,7 +654,7 @@ bool Sd2Card::writeStart(uint32_t blockNumber, const uint32_t eraseCount) {
  *
  * \return true for success, false for failure.
  */
-bool Sd2Card::writeStop() {
+bool DiskIODriver_SPI_SD::writeStop() {
   if (ENABLED(SDCARD_READONLY)) return false;
 
   bool success = false;
@@ -666,4 +670,4 @@ bool Sd2Card::writeStop() {
   return success;
 }
 
-#endif // SDSUPPORT
+#endif // NEED_SD2CARD_SPI
diff --git a/Marlin/src/sd/Sd2Card.h b/Marlin/src/sd/Sd2Card.h
index eb7f9bb2ca..e0dce02a02 100644
--- a/Marlin/src/sd/Sd2Card.h
+++ b/Marlin/src/sd/Sd2Card.h
@@ -35,47 +35,50 @@
 
 #include "SdFatConfig.h"
 #include "SdInfo.h"
+#include "disk_io_driver.h"
 
 #include <stdint.h>
 
-uint16_t const SD_INIT_TIMEOUT = 2000,    // init timeout ms
-               SD_ERASE_TIMEOUT = 10000,  // erase timeout ms
-               SD_READ_TIMEOUT = 300,     // read timeout ms
-               SD_WRITE_TIMEOUT = 600;    // write time out ms
+uint16_t const SD_INIT_TIMEOUT  = 2000,  // (ms) Init timeout
+               SD_ERASE_TIMEOUT = 10000, // (ms) Erase timeout
+               SD_READ_TIMEOUT  = 300,   // (ms) Read timeout
+               SD_WRITE_TIMEOUT = 600;   // (ms) Write timeout
 
 // SD card errors
-uint8_t const SD_CARD_ERROR_CMD0 = 0x01,                // timeout error for command CMD0 (initialize card in SPI mode)
-              SD_CARD_ERROR_CMD8 = 0x02,                // CMD8 was not accepted - not a valid SD card
-              SD_CARD_ERROR_CMD12 = 0x03,               // card returned an error response for CMD12 (write stop)
-              SD_CARD_ERROR_CMD17 = 0x04,               // card returned an error response for CMD17 (read block)
-              SD_CARD_ERROR_CMD18 = 0x05,               // card returned an error response for CMD18 (read multiple block)
-              SD_CARD_ERROR_CMD24 = 0x06,               // card returned an error response for CMD24 (write block)
-              SD_CARD_ERROR_CMD25 = 0x07,               // WRITE_MULTIPLE_BLOCKS command failed
-              SD_CARD_ERROR_CMD58 = 0x08,               // card returned an error response for CMD58 (read OCR)
-              SD_CARD_ERROR_ACMD23 = 0x09,              // SET_WR_BLK_ERASE_COUNT failed
-              SD_CARD_ERROR_ACMD41 = 0x0A,              // ACMD41 initialization process timeout
-              SD_CARD_ERROR_BAD_CSD = 0x0B,             // card returned a bad CSR version field
-              SD_CARD_ERROR_ERASE = 0x0C,               // erase block group command failed
-              SD_CARD_ERROR_ERASE_SINGLE_BLOCK = 0x0D,  // card not capable of single block erase
-              SD_CARD_ERROR_ERASE_TIMEOUT = 0x0E,       // Erase sequence timed out
-              SD_CARD_ERROR_READ = 0x0F,                // card returned an error token instead of read data
-              SD_CARD_ERROR_READ_REG = 0x10,            // read CID or CSD failed
-              SD_CARD_ERROR_READ_TIMEOUT = 0x11,        // timeout while waiting for start of read data
-              SD_CARD_ERROR_STOP_TRAN = 0x12,           // card did not accept STOP_TRAN_TOKEN
-              SD_CARD_ERROR_WRITE = 0x13,               // card returned an error token as a response to a write operation
-              SD_CARD_ERROR_WRITE_BLOCK_ZERO = 0x14,    // REMOVE - not used ... attempt to write protected block zero
-              SD_CARD_ERROR_WRITE_MULTIPLE = 0x15,      // card did not go ready for a multiple block write
-              SD_CARD_ERROR_WRITE_PROGRAMMING = 0x16,   // card returned an error to a CMD13 status check after a write
-              SD_CARD_ERROR_WRITE_TIMEOUT = 0x17,       // timeout occurred during write programming
-              SD_CARD_ERROR_SCK_RATE = 0x18,            // incorrect rate selected
-              SD_CARD_ERROR_INIT_NOT_CALLED = 0x19,     // init() not called
-              // 0x1A is unused now, it was: card returned an error for CMD59 (CRC_ON_OFF)
-              SD_CARD_ERROR_READ_CRC = 0x1B;            // invalid read CRC
+typedef enum : uint8_t {
+  SD_CARD_ERROR_CMD0               = 0x01, // Timeout error for command CMD0 (initialize card in SPI mode)
+  SD_CARD_ERROR_CMD8               = 0x02, // CMD8 was not accepted - not a valid SD card
+  SD_CARD_ERROR_CMD12              = 0x03, // Card returned an error response for CMD12 (write stop)
+  SD_CARD_ERROR_CMD17              = 0x04, // Card returned an error response for CMD17 (read block)
+  SD_CARD_ERROR_CMD18              = 0x05, // Card returned an error response for CMD18 (read multiple block)
+  SD_CARD_ERROR_CMD24              = 0x06, // Card returned an error response for CMD24 (write block)
+  SD_CARD_ERROR_CMD25              = 0x07, // WRITE_MULTIPLE_BLOCKS command failed
+  SD_CARD_ERROR_CMD58              = 0x08, // Card returned an error response for CMD58 (read OCR)
+  SD_CARD_ERROR_ACMD23             = 0x09, // SET_WR_BLK_ERASE_COUNT failed
+  SD_CARD_ERROR_ACMD41             = 0x0A, // ACMD41 initialization process timeout
+  SD_CARD_ERROR_BAD_CSD            = 0x0B, // Card returned a bad CSR version field
+  SD_CARD_ERROR_ERASE              = 0x0C, // Erase block group command failed
+  SD_CARD_ERROR_ERASE_SINGLE_BLOCK = 0x0D, // Card not capable of single block erase
+  SD_CARD_ERROR_ERASE_TIMEOUT      = 0x0E, // Erase sequence timed out
+  SD_CARD_ERROR_READ               = 0x0F, // Card returned an error token instead of read data
+  SD_CARD_ERROR_READ_REG           = 0x10, // Read CID or CSD failed
+  SD_CARD_ERROR_READ_TIMEOUT       = 0x11, // Timeout while waiting for start of read data
+  SD_CARD_ERROR_STOP_TRAN          = 0x12, // Card did not accept STOP_TRAN_TOKEN
+  SD_CARD_ERROR_WRITE              = 0x13, // Card returned an error token as a response to a write operation
+  SD_CARD_ERROR_WRITE_BLOCK_ZERO   = 0x14, // REMOVE - not used ... attempt to write protected block zero
+  SD_CARD_ERROR_WRITE_MULTIPLE     = 0x15, // Card did not go ready for a multiple block write
+  SD_CARD_ERROR_WRITE_PROGRAMMING  = 0x16, // Card returned an error to a CMD13 status check after a write
+  SD_CARD_ERROR_WRITE_TIMEOUT      = 0x17, // Timeout occurred during write programming
+  SD_CARD_ERROR_SCK_RATE           = 0x18, // Incorrect rate selected
+  SD_CARD_ERROR_INIT_NOT_CALLED    = 0x19, // Init() not called
+  // 0x1A is unused now, it was: card returned an error for CMD59 (CRC_ON_OFF)
+  SD_CARD_ERROR_READ_CRC = 0x1B             // Invalid read CRC
+} sd_error_code_t;
 
 // card types
-uint8_t const SD_CARD_TYPE_SD1  = 1,                    // Standard capacity V1 SD card
-              SD_CARD_TYPE_SD2  = 2,                    // Standard capacity V2 SD card
-              SD_CARD_TYPE_SDHC = 3;                    // High Capacity SD card
+uint8_t const SD_CARD_TYPE_SD1  = 1,        // Standard capacity V1 SD card
+              SD_CARD_TYPE_SD2  = 2,        // Standard capacity V2 SD card
+              SD_CARD_TYPE_SDHC = 3;        // High Capacity SD card
 
 /**
  * Define SOFTWARE_SPI to use bit-bang SPI
@@ -93,12 +96,11 @@ uint8_t const SD_CARD_TYPE_SD1  = 1,                    // Standard capacity V1
  * \class Sd2Card
  * \brief Raw access to SD and SDHC flash memory cards.
  */
-class Sd2Card {
+class DiskIODriver_SPI_SD : public DiskIODriver {
 public:
 
-  Sd2Card() : errorCode_(SD_CARD_ERROR_INIT_NOT_CALLED), type_(0) {}
+  DiskIODriver_SPI_SD() : errorCode_(SD_CARD_ERROR_INIT_NOT_CALLED), type_(0) {}
 
-  uint32_t cardSize();
   bool erase(uint32_t firstBlock, uint32_t lastBlock);
   bool eraseSingleBlockEnable();
 
@@ -106,7 +108,7 @@ public:
    *  Set SD error code.
    *  \param[in] code value for error code.
    */
-  inline void error(const uint8_t code) { errorCode_ = code; }
+  void error(const uint8_t code);
 
   /**
    * \return error code for last error. See Sd2Card.h for a list of error codes.
@@ -122,9 +124,15 @@ public:
    *
    * \return true for success or false for failure.
    */
-  bool init(const uint8_t sckRateID, const pin_t chipSelectPin);
+  bool init(const uint8_t sckRateID, const pin_t chipSelectPin) override;
 
-  bool readBlock(uint32_t block, uint8_t *dst);
+  bool setSckRate(const uint8_t sckRateID);
+
+  /**
+   * Return the card type: SD V1, SD V2 or SDHC
+   * \return 0 - SD V1, 1 - SD V2, or 3 - SDHC.
+   */
+  int type() const { return type_; }
 
   /**
    * Read a card's CID register. The CID contains card identification
@@ -145,24 +153,27 @@ public:
    *
    * \return true for success or false for failure.
    */
-  inline bool readCSD(csd_t *csd) { return readRegister(CMD9, csd); }
+  inline bool readCSD(csd_t *csd) override { return readRegister(CMD9, csd); }
 
-  bool readData(uint8_t *dst);
-  bool readStart(uint32_t blockNumber);
-  bool readStop();
-  bool setSckRate(const uint8_t sckRateID);
+  bool readData(uint8_t *dst) override;
+  bool readStart(uint32_t blockNumber) override;
+  bool readStop() override;
 
-  /**
-   * Return the card type: SD V1, SD V2 or SDHC
-   * \return 0 - SD V1, 1 - SD V2, or 3 - SDHC.
-   */
-  int type() const {return type_;}
-  bool writeBlock(uint32_t blockNumber, const uint8_t *src);
-  bool writeData(const uint8_t *src);
-  bool writeStart(uint32_t blockNumber, const uint32_t eraseCount);
-  bool writeStop();
+  bool writeData(const uint8_t *src) override;
+  bool writeStart(const uint32_t blockNumber, const uint32_t eraseCount) override;
+  bool writeStop() override;
+
+  bool readBlock(uint32_t block, uint8_t *dst) override;
+  bool writeBlock(uint32_t blockNumber, const uint8_t *src) override;
+
+  uint32_t cardSize() override;
+
+  bool isReady() override { return ready; };
+
+  void idle() override {}
 
 private:
+  bool ready = false;
   uint8_t chipSelectPin_,
           errorCode_,
           spiRate_,
diff --git a/Marlin/src/sd/Sd2Card_sdio.h b/Marlin/src/sd/Sd2Card_sdio.h
index 10fb757359..1580344805 100644
--- a/Marlin/src/sd/Sd2Card_sdio.h
+++ b/Marlin/src/sd/Sd2Card_sdio.h
@@ -23,17 +23,33 @@
 
 #include "../inc/MarlinConfig.h"
 
-#if ENABLED(SDIO_SUPPORT)
+#include "SdInfo.h"
+#include "disk_io_driver.h"
 
 bool SDIO_Init();
 bool SDIO_ReadBlock(uint32_t block, uint8_t *dst);
 bool SDIO_WriteBlock(uint32_t block, const uint8_t *src);
 
-class Sd2Card {
+class DiskIODriver_SDIO : public DiskIODriver {
   public:
-    bool init(uint8_t sckRateID = 0, uint8_t chipSelectPin = 0) { return SDIO_Init(); }
-    bool readBlock(uint32_t block, uint8_t *dst) { return SDIO_ReadBlock(block, dst); }
-    bool writeBlock(uint32_t block, const uint8_t *src) { return SDIO_WriteBlock(block, src); }
-};
+    bool init(const uint8_t sckRateID=0, const pin_t chipSelectPin=0) override { return SDIO_Init(); }
 
-#endif // SDIO_SUPPORT
+    bool readCSD(csd_t *csd)                              override { return false; }
+
+    bool readStart(const uint32_t block)                  override { return false; }
+    bool readData(uint8_t *dst)                           override { return false; }
+    bool readStop()                                       override { return false; }
+
+    bool writeStart(const uint32_t block, const uint32_t) override { return false; }
+    bool writeData(const uint8_t *src)                    override { return false; }
+    bool writeStop()                                      override { return false; }
+
+    bool readBlock(uint32_t block, uint8_t *dst)          override { return SDIO_ReadBlock(block, dst); }
+    bool writeBlock(uint32_t block, const uint8_t *src)   override { return SDIO_WriteBlock(block, src); }
+
+    uint32_t cardSize()                                   override { return 0; }
+
+    bool isReady()                                        override { return true; }
+
+    void idle()                                           override {}
+};
diff --git a/Marlin/src/sd/SdFatConfig.h b/Marlin/src/sd/SdFatConfig.h
index 13ac3a7487..dfba641295 100644
--- a/Marlin/src/sd/SdFatConfig.h
+++ b/Marlin/src/sd/SdFatConfig.h
@@ -39,7 +39,7 @@
  *
  * Each card requires about 550 bytes of SRAM so use of a Mega is recommended.
  */
-#define USE_MULTIPLE_CARDS 0
+#define USE_MULTIPLE_CARDS 0 //TODO? ENABLED(MULTI_VOLUME)
 
 /**
  * Call flush for endl if ENDL_CALLS_FLUSH is nonzero
diff --git a/Marlin/src/sd/SdVolume.cpp b/Marlin/src/sd/SdVolume.cpp
index 7fcebd640d..1b1fdc5a7c 100644
--- a/Marlin/src/sd/SdVolume.cpp
+++ b/Marlin/src/sd/SdVolume.cpp
@@ -41,10 +41,10 @@
   // raw block cache
   uint32_t SdVolume::cacheBlockNumber_;  // current block number
   cache_t  SdVolume::cacheBuffer_;       // 512 byte cache for Sd2Card
-  Sd2Card* SdVolume::sdCard_;            // pointer to SD card object
+  DiskIODriver *SdVolume::sdCard_;       // pointer to SD card object
   bool     SdVolume::cacheDirty_;        // cacheFlush() will write block if true
   uint32_t SdVolume::cacheMirrorBlock_;  // mirror  block for second FAT
-#endif  // USE_MULTIPLE_CARDS
+#endif
 
 // find a contiguous group of clusters
 bool SdVolume::allocContiguous(uint32_t count, uint32_t *curCluster) {
@@ -326,7 +326,7 @@ int32_t SdVolume::freeClusterCount() {
  * Reasons for failure include not finding a valid partition, not finding a valid
  * FAT file system in the specified partition or an I/O error.
  */
-bool SdVolume::init(Sd2Card* dev, uint8_t part) {
+bool SdVolume::init(DiskIODriver* dev, uint8_t part) {
   uint32_t totalBlocks, volumeStartBlock = 0;
   fat32_boot_t *fbs;
 
diff --git a/Marlin/src/sd/SdVolume.h b/Marlin/src/sd/SdVolume.h
index c2eaf0bd13..b8e70ca9d7 100644
--- a/Marlin/src/sd/SdVolume.h
+++ b/Marlin/src/sd/SdVolume.h
@@ -36,9 +36,11 @@
 
 #if ENABLED(USB_FLASH_DRIVE_SUPPORT)
   #include "usb_flashdrive/Sd2Card_FlashDrive.h"
-#elif ENABLED(SDIO_SUPPORT)
+#endif
+
+#if NEED_SD2CARD_SDIO
   #include "Sd2Card_sdio.h"
-#else
+#elif NEED_SD2CARD_SPI
   #include "Sd2Card.h"
 #endif
 
@@ -47,6 +49,7 @@
 
 //==============================================================================
 // SdVolume class
+
 /**
  * \brief Cache for an SD data block
  */
@@ -84,14 +87,14 @@ class SdVolume {
    * Initialize a FAT volume.  Try partition one first then try super
    * floppy format.
    *
-   * \param[in] dev The Sd2Card where the volume is located.
+   * \param[in] dev The DiskIODriver where the volume is located.
    *
    * \return true for success, false for failure.
    * Reasons for failure include not finding a valid partition, not finding
    * a valid FAT file system or an I/O error.
    */
-  bool init(Sd2Card *dev) { return init(dev, 1) ? true : init(dev, 0); }
-  bool init(Sd2Card *dev, uint8_t part);
+  bool init(DiskIODriver *dev) { return init(dev, 1) || init(dev, 0); }
+  bool init(DiskIODriver *dev, uint8_t part);
 
   // inline functions that return volume info
   uint8_t blocksPerCluster() const { return blocksPerCluster_; } //> \return The volume's cluster size in blocks.
@@ -112,10 +115,10 @@ class SdVolume {
   uint32_t rootDirStart() const { return rootDirStart_; }
 
   /**
-   * Sd2Card object for this volume
-   * \return pointer to Sd2Card object.
+   * DiskIODriver object for this volume
+   * \return pointer to DiskIODriver object.
    */
-  Sd2Card* sdCard() { return sdCard_; }
+  DiskIODriver* sdCard() { return sdCard_; }
 
   /**
    * Debug access to FAT table
@@ -138,13 +141,13 @@ class SdVolume {
   #if USE_MULTIPLE_CARDS
     cache_t cacheBuffer_;        // 512 byte cache for device blocks
     uint32_t cacheBlockNumber_;  // Logical number of block in the cache
-    Sd2Card *sdCard_;            // Sd2Card object for cache
+    DiskIODriver *sdCard_;       // DiskIODriver object for cache
     bool cacheDirty_;            // cacheFlush() will write block if true
     uint32_t cacheMirrorBlock_;  // block number for mirror FAT
   #else
     static cache_t cacheBuffer_;        // 512 byte cache for device blocks
     static uint32_t cacheBlockNumber_;  // Logical number of block in the cache
-    static Sd2Card *sdCard_;            // Sd2Card object for cache
+    static DiskIODriver *sdCard_;       // DiskIODriver object for cache
     static bool cacheDirty_;            // cacheFlush() will write block if true
     static uint32_t cacheMirrorBlock_;  // block number for mirror FAT
   #endif
diff --git a/Marlin/src/sd/cardreader.cpp b/Marlin/src/sd/cardreader.cpp
index 07a57cc658..a54884bec1 100644
--- a/Marlin/src/sd/cardreader.cpp
+++ b/Marlin/src/sd/cardreader.cpp
@@ -120,7 +120,16 @@ uint8_t CardReader::workDirDepth;
 
 #endif // SDCARD_SORT_ALPHA
 
-Sd2Card CardReader::sd2card;
+#if SHARED_VOLUME_IS(USB_FLASH_DRIVE) || ENABLED(USB_FLASH_DRIVE_SUPPORT)
+  DiskIODriver_USBFlash CardReader::media_usbFlashDrive;
+#endif
+#if NEED_SD2CARD_SDIO
+  DiskIODriver_SDIO CardReader::media_sdio;
+#elif NEED_SD2CARD_SPI
+  DiskIODriver_SPI_SD CardReader::media_sd_spi;
+#endif
+
+DiskIODriver* CardReader::driver = nullptr;
 SdVolume CardReader::volume;
 SdFile CardReader::file;
 
@@ -133,6 +142,16 @@ SdFile CardReader::file;
 uint32_t CardReader::filesize, CardReader::sdpos;
 
 CardReader::CardReader() {
+  changeMedia(&
+    #if SHARED_VOLUME_IS(SD_ONBOARD)
+      media_sd_spi
+    #elif SHARED_VOLUME_IS(USB_FLASH_DRIVE) || ENABLED(USB_FLASH_DRIVE_SUPPORT)
+      media_usbFlashDrive
+    #else
+      TERN(SDIO_SUPPORT, media_sdio, media_sd_spi)
+    #endif
+  );
+
   #if ENABLED(SDCARD_SORT_ALPHA)
     sort_count = 0;
     #if ENABLED(SDSORT_GCODE)
@@ -383,12 +402,12 @@ void CardReader::mount() {
   flag.mounted = false;
   if (root.isOpen()) root.close();
 
-  if (!sd2card.init(SD_SPI_SPEED, SDSS)
+  if (!driver->init(SD_SPI_SPEED, SDSS)
     #if defined(LCD_SDSS) && (LCD_SDSS != SDSS)
-      && !sd2card.init(SD_SPI_SPEED, LCD_SDSS)
+      && !driver->init(SD_SPI_SPEED, LCD_SDSS)
     #endif
   ) SERIAL_ECHO_MSG(STR_SD_INIT_FAIL);
-  else if (!volume.init(&sd2card))
+  else if (!volume.init(driver))
     SERIAL_ERROR_MSG(STR_SD_VOL_INIT_FAIL);
   else if (!root.openRoot(&volume))
     SERIAL_ERROR_MSG(STR_SD_OPENROOT_FAIL);
diff --git a/Marlin/src/sd/cardreader.h b/Marlin/src/sd/cardreader.h
index f1002e1dab..5fdd1222ae 100644
--- a/Marlin/src/sd/cardreader.h
+++ b/Marlin/src/sd/cardreader.h
@@ -42,6 +42,29 @@ extern const char M23_STR[], M24_STR[];
 #define MAXPATHNAMELENGTH  (1 + (MAXDIRNAMELENGTH + 1) * (MAX_DIR_DEPTH) + 1 + FILENAME_LENGTH) // "/" + N * ("ADIRNAME/") + "filename.ext"
 
 #include "SdFile.h"
+#include "disk_io_driver.h"
+
+#if ENABLED(USB_FLASH_DRIVE_SUPPORT)
+  #include "usb_flashdrive/Sd2Card_FlashDrive.h"
+#endif
+
+#if NEED_SD2CARD_SDIO
+  #include "Sd2Card_sdio.h"
+#elif NEED_SD2CARD_SPI
+  #include "Sd2Card.h"
+#endif
+
+#if ENABLED(MULTI_VOLUME)
+  #define SV_SD_ONBOARD      1
+  #define SV_USB_FLASH_DRIVE 2
+  #define _VOLUME_ID(N) _CAT(SV_, N)
+  #define SHARED_VOLUME_IS(N) (DEFAULT_SHARED_VOLUME == _VOLUME_ID(N))
+  #if !SHARED_VOLUME_IS(SD_ONBOARD) && !SHARED_VOLUME_IS(USB_FLASH_DRIVE)
+    #error "DEFAULT_SHARED_VOLUME must be either SD_ONBOARD or USB_FLASH_DRIVE."
+  #endif
+#else
+  #define SHARED_VOLUME_IS(...) 0
+#endif
 
 typedef struct {
   bool saving:1,
@@ -80,6 +103,8 @@ public:
 
   CardReader();
 
+  static void changeMedia(DiskIODriver *_driver) { driver = _driver; }
+
   static SdFile getroot() { return root; }
 
   static void mount();
@@ -171,7 +196,8 @@ public:
   static inline int16_t read(void *buf, uint16_t nbyte) { return file.isOpen() ? file.read(buf, nbyte) : -1; }
   static inline int16_t write(void *buf, uint16_t nbyte) { return file.isOpen() ? file.write(buf, nbyte) : -1; }
 
-  static Sd2Card& getSd2Card() { return sd2card; }
+  // TODO: rename to diskIODriver()
+  static DiskIODriver* diskIODriver() { return driver; }
 
   #if ENABLED(AUTO_REPORT_SD_STATUS)
     //
@@ -181,6 +207,15 @@ public:
     static AutoReporter<AutoReportSD> auto_reporter;
   #endif
 
+  #if SHARED_VOLUME_IS(USB_FLASH_DRIVE) || ENABLED(USB_FLASH_DRIVE_SUPPORT)
+    static DiskIODriver_USBFlash media_usbFlashDrive;
+  #endif
+  #if NEED_SD2CARD_SDIO
+    static DiskIODriver_SDIO media_sdio;
+  #elif NEED_SD2CARD_SPI
+    static DiskIODriver_SPI_SD media_sd_spi;
+  #endif
+
 private:
   //
   // Working directory and parents
@@ -236,7 +271,7 @@ private:
         #if ENABLED(SDSORT_DYNAMIC_RAM)
           static uint8_t *isDir;
         #elif ENABLED(SDSORT_CACHE_NAMES) || DISABLED(SDSORT_USES_STACK)
-          static uint8_t isDir[(SDSORT_LIMIT+7)>>3];
+          static uint8_t isDir[(SDSORT_LIMIT + 7) >> 3];
         #endif
       #endif
 
@@ -244,7 +279,7 @@ private:
 
   #endif // SDCARD_SORT_ALPHA
 
-  static Sd2Card sd2card;
+  static DiskIODriver *driver;
   static SdVolume volume;
   static SdFile file;
 
@@ -275,7 +310,7 @@ private:
 };
 
 #if ENABLED(USB_FLASH_DRIVE_SUPPORT)
-  #define IS_SD_INSERTED() Sd2Card::isInserted()
+  #define IS_SD_INSERTED() DiskIODriver_USBFlash::isInserted()
 #elif PIN_EXISTS(SD_DETECT)
   #define IS_SD_INSERTED() (READ(SD_DETECT_PIN) == SD_DETECT_STATE)
 #else
diff --git a/Marlin/src/sd/disk_io_driver.h b/Marlin/src/sd/disk_io_driver.h
new file mode 100644
index 0000000000..73c12efcfa
--- /dev/null
+++ b/Marlin/src/sd/disk_io_driver.h
@@ -0,0 +1,67 @@
+/**
+ * Marlin 3D Printer Firmware
+ * Copyright (c) 2021 MarlinFirmware [https://github.com/MarlinFirmware/Marlin]
+ *
+ * Based on Sprinter and grbl.
+ * Copyright (c) 2011 Camiel Gubbels / Erik van der Zalm
+ *
+ * This program is free software: you can redistribute it and/or modify
+ * it under the terms of the GNU General Public License as published by
+ * the Free Software Foundation, either version 3 of the License, or
+ * (at your option) any later version.
+ *
+ * This program is distributed in the hope that it will be useful,
+ * but WITHOUT ANY WARRANTY; without even the implied warranty of
+ * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+ * GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License
+ * along with this program.  If not, see <https://www.gnu.org/licenses/>.
+ *
+ */
+#pragma once
+
+#include <stdint.h>
+
+/**
+ * DiskIO Interace
+ *
+ * Interface for low level disk io
+ */
+class DiskIODriver {
+public:
+  /**
+   * Initialize an SD flash memory card with default clock rate and chip
+   * select pin.  See sd2Card::init(uint8_t sckRateID, uint8_t chipSelectPin).
+   *
+   * \return true for success or false for failure.
+   */
+  virtual bool init(const uint8_t sckRateID, const pin_t chipSelectPin) = 0; //TODO: only for SPI
+
+  /**
+   * Read a card's CSD register. The CSD contains Card-Specific Data that
+   * provides information regarding access to the card's contents.
+   *
+   * \param[out] csd pointer to area for returned data.
+   *
+   * \return true for success or false for failure.
+   */
+  virtual bool readCSD(csd_t* csd) = 0;
+
+  virtual bool readStart(const uint32_t block) = 0;
+  virtual bool readData(uint8_t* dst) = 0;
+  virtual bool readStop() = 0;
+
+  virtual bool writeStart(const uint32_t block, const uint32_t) = 0;
+  virtual bool writeData(const uint8_t* src) = 0;
+  virtual bool writeStop() = 0;
+
+  virtual bool readBlock(uint32_t block, uint8_t* dst) = 0;
+  virtual bool writeBlock(uint32_t blockNumber, const uint8_t* src) = 0;
+
+  virtual uint32_t cardSize() = 0;
+
+  virtual bool isReady() = 0;
+
+  virtual void idle() = 0;
+};
diff --git a/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.cpp b/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.cpp
index dc9efcb672..1975418415 100644
--- a/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.cpp
+++ b/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.cpp
@@ -121,7 +121,7 @@ static enum {
   uint32_t lun0_capacity;
 #endif
 
-bool Sd2Card::usbStartup() {
+bool DiskIODriver_USBFlash::usbStartup() {
   if (state <= DO_STARTUP) {
     SERIAL_ECHOPGM("Starting USB host...");
     if (!UHS_START) {
@@ -147,7 +147,7 @@ bool Sd2Card::usbStartup() {
 // the USB library to monitor for such events. This function also takes care
 // of initializing the USB library for the first time.
 
-void Sd2Card::idle() {
+void DiskIODriver_USBFlash::idle() {
   usb.Task();
 
   const uint8_t task_state = usb.getUsbTaskState();
@@ -258,16 +258,16 @@ void Sd2Card::idle() {
 
 // Marlin calls this function to check whether an USB drive is inserted.
 // This is equivalent to polling the SD_DETECT when using SD cards.
-bool Sd2Card::isInserted() {
+bool DiskIODriver_USBFlash::isInserted() {
   return state == MEDIA_READY;
 }
 
-bool Sd2Card::isReady() {
-  return state > DO_STARTUP;
+bool DiskIODriver_USBFlash::isReady() {
+  return state > DO_STARTUP && usb.getUsbTaskState() == UHS_STATE(RUNNING);
 }
 
 // Marlin calls this to initialize an SD card once it is inserted.
-bool Sd2Card::init(const uint8_t, const pin_t) {
+bool DiskIODriver_USBFlash::init(const uint8_t, const pin_t) {
   if (!isInserted()) return false;
 
   #if USB_DEBUG >= 1
@@ -286,7 +286,7 @@ bool Sd2Card::init(const uint8_t, const pin_t) {
 }
 
 // Returns the capacity of the card in blocks.
-uint32_t Sd2Card::cardSize() {
+uint32_t DiskIODriver_USBFlash::cardSize() {
   if (!isInserted()) return false;
   #if USB_DEBUG < 3
     const uint32_t
@@ -295,7 +295,7 @@ uint32_t Sd2Card::cardSize() {
   return lun0_capacity;
 }
 
-bool Sd2Card::readBlock(uint32_t block, uint8_t *dst) {
+bool DiskIODriver_USBFlash::readBlock(uint32_t block, uint8_t *dst) {
   if (!isInserted()) return false;
   #if USB_DEBUG >= 3
     if (block >= lun0_capacity) {
@@ -309,7 +309,7 @@ bool Sd2Card::readBlock(uint32_t block, uint8_t *dst) {
   return bulk.Read(0, block, 512, 1, dst) == 0;
 }
 
-bool Sd2Card::writeBlock(uint32_t block, const uint8_t *src) {
+bool DiskIODriver_USBFlash::writeBlock(uint32_t block, const uint8_t *src) {
   if (!isInserted()) return false;
   #if USB_DEBUG >= 3
     if (block >= lun0_capacity) {
diff --git a/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.h b/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.h
index 320678d091..3390bc51be 100644
--- a/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.h
+++ b/Marlin/src/sd/usb_flashdrive/Sd2Card_FlashDrive.h
@@ -27,6 +27,7 @@
  */
 #include "../SdFatConfig.h"
 #include "../SdInfo.h"
+#include "../disk_io_driver.h"
 
 #if DISABLED(USE_OTG_USB_HOST)
   /**
@@ -46,7 +47,7 @@
   #endif
 #endif
 
-class Sd2Card {
+class DiskIODriver_USBFlash : public DiskIODriver {
   private:
     uint32_t pos;
 
@@ -54,25 +55,26 @@ class Sd2Card {
 
   public:
     static bool usbStartup();
-
-    bool init(const uint8_t sckRateID=0, const pin_t chipSelectPin=TERN(USE_OTG_USB_HOST, 0, SD_CHIP_SELECT_PIN));
-
-    static void idle();
-
-    inline bool readStart(const uint32_t block)                  { pos = block; return isReady(); }
-    inline bool readData(uint8_t *dst)                           { return readBlock(pos++, dst); }
-    inline bool readStop() const                                 { return true; }
-
-    inline bool writeStart(const uint32_t block, const uint32_t) { pos = block; return isReady(); }
-    inline bool writeData(uint8_t *src)                          { return writeBlock(pos++, src); }
-    inline bool writeStop() const                                { return true; }
-
-    bool readBlock(uint32_t block, uint8_t *dst);
-    bool writeBlock(uint32_t blockNumber, const uint8_t *src);
-
-    bool readCSD(csd_t*)                                         { return true; }
-
-    uint32_t cardSize();
     static bool isInserted();
-    bool isReady();
+
+    bool init(const uint8_t sckRateID=0, const pin_t chipSelectPin=TERN(USE_OTG_USB_HOST, 0, SD_CHIP_SELECT_PIN)) override;
+
+    inline bool readCSD(csd_t*)                                  override { return true; }
+
+    inline bool readStart(const uint32_t block)                  override { pos = block; return isReady(); }
+    inline bool readData(uint8_t *dst)                           override { return readBlock(pos++, dst); }
+    inline bool readStop()                                       override { return true; }
+
+    inline bool writeStart(const uint32_t block, const uint32_t) override { pos = block; return isReady(); }
+    inline bool writeData(const uint8_t *src)                    override { return writeBlock(pos++, src); }
+    inline bool writeStop()                                      override { return true; }
+
+    bool readBlock(uint32_t block, uint8_t *dst) override;
+    bool writeBlock(uint32_t blockNumber, const uint8_t *src) override;
+
+    uint32_t cardSize() override;
+
+    bool isReady() override;
+
+    void idle() override;
 };